⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904104 | 0.70 | TDP2 (0.35) | — | |
| SCHEMBL1509853 | 0.69 | — | — | |
| SCHEMBL41851 | 0.69 | — | — | |
| Water SCHEMBL7264692 | 0.67 | TDP2 (0.39) | — | |
| SCHEMBL407972 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL10924919 | 0.66 | — | — | |
| SCHEMBL14964727 | 0.65 | TDP2 (0.38) | — | |
| SCHEMBL5779557 | 0.65 | — | — | |
| SCHEMBL251099 | 0.65 | — | — | |
| SCHEMBL22096616 | 0.64 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37556-E1 | (ALKOXYPHENYL)THIAZOLE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | claimed |
| US-5643932-A | PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | claimed |
| EP-0643715-A1 | PROTECTED PHOSPHONOALKYL PHENYLALANINE COMPOUNDS FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-03-22 | — | — | EP | claimed |
| WO-1993007158-A1 | PROTECTED PHOSPHONOALKYL PHENYLALANINE COMPOUNDS FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-04-15 | — | — | WO | claimed |
| US-5200546-A | PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-04-06 | — | — | US | claimed |