Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | ESRRG | P62508 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14719491 | 0.79 | AR (0.49) | ARHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL95440 | 0.73 | MEN1 (0.35) | TSHRTP53ACACBARMEN1 | |
| SCHEMBL27946212 | 0.73 | HTT (0.36) | TSHRARESRRGESR1CYP3A4 | |
| SCHEMBL8007519 | 0.69 | ESR1 (0.46) | TSHRTP53RECQLACACBAR | |
| SCHEMBL4410147 | 0.69 | TSHR (0.51) | TSHRTP53RECQLACACBGRB2 | |
| SCHEMBL4410153 | 0.69 | AR (0.49) | TSHRTP53RECQLGRB2AR | |
| SCHEMBL41070 | 0.68 | ESR1 (0.44) | TSHRTP53ACACBARESRRG | |
| SCHEMBL21812152 | 0.68 | TSHR (0.37) | TSHRTP53ACACBCYP3A4NPC1 | |
| SCHEMBL28305244 | 0.65 | THRB (0.47) | TSHRTP53RECQLARESRRG | |
| SCHEMBL5665294 | 0.65 | ESR1 (0.41) | TSHRTP53ESR1CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353039-B1 | CROSSLINKING POLYMER COMPOSITES AND TRANSPARENT GLASS | IVOCLAR AG (LI) | 2002-03-05 | — | — | US | claimed |