Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11881601 | 0.95 | — | — | |
| Acetic Acid SCHEMBL312459 | 0.95 | — | — | |
| Acetic Acid SCHEMBL29039833 | 0.95 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL11881095 | 0.91 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL28339603 | 0.90 | — | — | |
| Acetic Acid SCHEMBL1632560 | 0.90 | — | — | |
| Acetic Acid SCHEMBL3961679 | 0.90 | — | — | |
| SCHEMBL5180151 | 0.89 | — | — | |
| SCHEMBL11026359 | 0.89 | — | — | |
| SCHEMBL1331275 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304080-B | Production process of dimethyl thiotoluene diamine | 东营海瑞宝新材料有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117304080-A | Production process of dimethyl thiotoluene diamine | 东营海瑞宝新材料有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-116640292-A | Preparation method of low-free polyurethane prepolymer with low crosslinking and high performance and capable of being distilled at low temperature | 赢聚化学技术研发(南京)有限公司 | 2023-08-25 | — | — | CN | claimed |
| US-4281184-A | REACTIC ACETIC ANHYDRIDE AND HYDROCHLORIC ACID | FONDAZIONE DENORA (IT) | 1981-07-28 | — | — | US | claimed |
| US-20240174702-A1 | SOLID FORMS OF A COMPOUND FOR MODULATING COT | GILEAD SCIENCES, INC. | 2024-05-30 | — | — | US | disclosed |
| CN-117304080-B | Production process of dimethyl thiotoluene diamine | 东营海瑞宝新材料有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117304080-A | Production process of dimethyl thiotoluene diamine | 东营海瑞宝新材料有限公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2023220123-A1 | SOLID FORMS OF A COMPOUND FOR MODULATING COT | GILEAD SCIENCES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-116640292-A | Preparation method of low-free polyurethane prepolymer with low crosslinking and high performance and capable of being distilled at low temperature | 赢聚化学技术研发(南京)有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-109988220-B | Preparation method of green synthetic tanshinone IIA sodium sulfonate | 上海星叶医药科技有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-105541599-A | Synthetic method for drug intermediate 4-p-methoxyphenyl-4-ketobutyric acid of pyridazinone | CHENGDU CARDIFF SCIENCE AND TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |
| EP-1189875-A2 | MONO AND MULTIFUNCTIONAL ALKOXYAMINES FOR THE PREPARATION OF FUNCTIONALIZED MACROMERS | Ciba SC Holding AG (CH) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001002345-A2 | MONO AND MULTIFUNCTIONAL ALKOXYAMINES FOR THE PREPARATION OF FUNCTIONALIZED MACROMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-01-11 | — | — | WO | disclosed |
| US-5766841-A | USING ENZYME | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0523046-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991006539-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | disclosed |
| US-4281184-A | REACTIC ACETIC ANHYDRIDE AND HYDROCHLORIC ACID | FONDAZIONE DENORA (IT) | 1981-07-28 | — | — | US | disclosed |
| US-3996270-A | Intermediate for Gossyplure, the sex pheromone of the pink bollworm | STORY CHEMICAL CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |