Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593476 | 0.97 | KMT2A (0.55) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL28458382 | 0.97 | KMT2A (0.55) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL15631616 | 0.87 | CHUK (0.47) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL874481 | 0.86 | KMT2A (0.56) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL29416622 | 0.79 | PIM1 (0.58) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL2588529 | 0.79 | PIM1 (0.58) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL21398285 | 0.78 | IDO1 (0.48) | KMT2AALDH1A1CHUKIDO1TDO2 | |
| SCHEMBL25625940 | 0.77 | KMT2A (0.64) | KMT2AALDH1A1TSHRHPGDPIM1 | |
| SCHEMBL47040 | 0.76 | PIM1 (0.51) | KMT2AALDH1A1HPGDPIM1TBK1 | |
| SCHEMBL30593469 | 0.76 | PIM1 (0.51) | KMT2AALDH1A1HPGDPIM1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |