SCHEMBL29416622

SCHEMBL29416622

O=c1c2cc(Br)ccc2oc2ccc(Br)cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.58
SMN1; SMN2 Q16637 4/20 0.57
MAPT P10636 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
GFER P55789 1/20 0.57
PTPN1 P18031 1/20 0.53
KMT2A Q03164 1/20 0.53
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
GABRP O00591 4/20 0.51
GABRD O14764 4/20 0.51
GABRA1 P14867 4/20 0.51
GABRB1 P18505 4/20 0.51
GABRG2 P18507 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2588529 1.00 PIM1 (0.58) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL47040 0.92 PIM1 (0.51) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL30593469 0.92 PIM1 (0.51) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL2592127 0.90 MAOA (0.67) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL30284875 0.90 MAOA (0.67) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL19217398 0.89 CSNK2A2 (0.62) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL2000388 0.89 PIM1 (0.49) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL2521053 0.89 TTR (0.59) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL2000612 0.87 GABRP (0.49) PIM1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL26936310 0.86 PIM1 (0.46) PIM1SMN1; SMN2MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290438-A Diamine precursor, polyimide and transparent polyimide film based on spiro-bisxanthene structure and manufacturing method thereof 大连理工大学 2024-07-05 CN disclosed
CN-117964635-B Organic luminescent material based on spiro thioxanthene and preparation method and application thereof 大连理工大学 2024-07-05 CN disclosed
CN-117964635-A Organic luminescent material based on spiro thioxanthene and preparation method and application thereof 大连理工大学 2024-05-03 CN disclosed
CN-111484468-B Compound for preparing organic photoelectric device 烟台显华光电材料研究院有限公司 2023-09-22 CN disclosed
CN-112010843-B Compound for preparing organic photoelectric device and application thereof 烟台显华光电材料研究院有限公司 2022-03-08 CN disclosed