Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164222 | 0.81 | TDP1 (0.42) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL11329385 | 0.79 | ALDH1A1 (0.33) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8361963 | 0.76 | TSHR (0.55) | TSHRALDH1A1 | |
| SCHEMBL25446318 | 0.75 | MGAM (0.52) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL11330248 | 0.74 | MGAM (0.38) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL15131420 | 0.73 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28102220 | 0.73 | MGAM (0.40) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5474408 | 0.72 | TSHR (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL21955400 | 0.72 | MGAM (0.52) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL96087 | 0.72 | MGAM (0.43) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348623-B2 | (CO)POLYMERS OF 1-ACETOXY-2-METHOXY-3-BUTENE FOR EXAMPLE; CAN COPOLYMERIZE WITH VINYL ACETATE; REACTING ACETOACETOXY FUNCTIONAL POLYMER WITH AMMONIA OR PRIMARY OR SECONDARY AMINES TO FORM ENAMINE FUNCTIONAL POLYMERS; COATINGS | EASTMAN CHEMICAL COMPANY | 2002-02-19 | — | — | US | disclosed |
| US-20010051690-A1 | Polymers of 3-butene esters, their preparation and use | EASTMAN CHEMICAL COMPANY | 2001-12-13 | — | — | US | disclosed |
| US-6228949-B1 | ACETOACETOXY-DERIVATIZED HOMO OR CO-POLY(3,4-EPOXY-1-BUTENE) WHEREBY THE ACETOACETOXY GROUPS HAVE BEEN REACTED WITH AMMONIA, PRIMARY OR SECONDARY AMINE TO FORM ENAMINE FUNCTIONAL GROUPS; HIGH MOLECULAR WEIGHT COATINGS, ADHESIVES | EASTMAN CHEMICAL COMPANY | 2001-05-08 | — | — | US | disclosed |
| US-6160057-A | Polymers of 3-butene esters, their preparation and use | EASTMAN CHEMICAL COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-6121400-A | FREE-RADICAL POLYMERIZATION PRODUCT; FOR COATING COMPOSITIONS SUCH AS INKS, ADHESIVES, PAINTS, AND FILMS | EASTMAN CHEMICAL COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| US-6121399-A | Polymers of 3-butene esters, their preparation and use | EASTMAN CHEMICAL COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| EP-1023340-A1 | POLYMERS OF 3-BUTENE ESTERS, THEIR PREPARATION AND USE | EASTMAN CHEMICAL COMPANY (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999020666-A1 | POLYMERS OF 3-BUTENE ESTERS, THEIR PREPARATION AND USE | EASTMAN CHEMICAL COMPANY (US) | 1999-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051690-A1 | Polymers of 3-butene esters, their preparation and use | CCNT1, C1S, H1-3 | MGAM 4380/4885GAA 4688/4885SI 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.