Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CDC25A | P30304 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | CDC25C | P30307 | 3/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196901 | 0.88 | MAPT (0.64) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL6200789 | 0.85 | MAPT (0.57) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL7501066 | 0.85 | MAPT (0.59) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL6200730 | 0.81 | MAPT (0.55) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL6198593 | 0.80 | MAPT (0.52) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL6194082 | 0.80 | MAPT (0.60) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL6199558 | 0.80 | CYP1A1 (0.61) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL15668432 | 0.79 | ALDH1A1 (0.51) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| SCHEMBL8525270 | 0.77 | SMN1; SMN2 (0.70) | MAPTNPC1RAB9AMMP12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6202875 | 0.76 | MAPT (0.64) | MAPTNPC1RAB9AMMP12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37556-E1 | (ALKOXYPHENYL)THIAZOLE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6080764-A | PROTECTING VARIOUS TISSUE CELLS FROM DISTURBANCES ASSOCIATED WITH ISCHEMIA AND BLOOD REPERFUSION IN HEART, BRAIN, KIDNEY, LUNG AND DIGESTIVE TRACT BY INHIBITING SUPEROXIDE-RELEASE BY NEUTROPHILIC LEUKOCYTES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |