Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7711386 | 0.99 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL7708368 | 0.90 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL7708492 | 0.89 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL7711449 | 0.86 | ABCB1 (0.58) | — | |
| SCHEMBL7708513 | 0.86 | MAPT (0.53) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL7705089 | 0.85 | MAPT (0.55) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL7708545 | 0.85 | GAA (0.57) | ALDH1A1MAPK1GAAMAPT | |
| SCHEMBL7987892 | 0.83 | MAPT (0.69) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL7713493 | 0.82 | MEN1 (0.52) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL7708335 | 0.82 | MAPT (0.71) | ALDH1A1MEN1KMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358515-B2 | ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | claimed |