Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | PTPRB | P23467 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2086545 | 0.78 | FFAR4 (0.45) | LMNAHPGDPTPN1MEN1KMT2A | |
| SCHEMBL2086547 | 0.78 | FFAR4 (0.45) | LMNAHPGDPTPN1MEN1KMT2A | |
| SCHEMBL7975332 | 0.75 | PTPN1 (0.64) | PTPN1PTPRBPTPN2PTPRASMN1; SMN2 | |
| SCHEMBL27385611 | 0.74 | PTPN1 (0.56) | PTPN1PTPRBPTPN2PTPRAMEN1 | |
| SCHEMBL2086116 | 0.73 | PTGER4 (0.43) | LMNAHPGDPTPN1MEN1KMT2A | |
| SCHEMBL2086118 | 0.73 | PTGER4 (0.43) | LMNAHPGDPTPN1MEN1KMT2A | |
| SCHEMBL17460412 | 0.73 | ALDH1A1 (0.56) | LMNAPTPN1PTPRBPTPN2PTPRA | |
| SCHEMBL6081447 | 0.73 | FFAR4 (0.54) | LMNAHPGDPTPN1MEN1KMT2A | |
| SCHEMBL2088361 | 0.72 | FFAR4 (0.43) | LMNAHPGDPTPN1MEN1KMT2A | |
| SCHEMBL2088362 | 0.72 | FFAR4 (0.43) | LMNAHPGDPTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344449-B1 | HEADACHE AND MORPHINE DEPENDENCE | DR. KARL THOMAE GMBH (DE) | 2002-02-05 | — | — | US | disclosed |