Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4469021 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6904860 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6672361 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8678390 | 0.78 | — | — | |
| SCHEMBL4577587 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL273193 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7766839 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL8391331 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL29213855 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9077192 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353071-B1 | DESICCATING MIXTURE OF ALUMINOXANE AND SOLVENT TO PRODUCE SOLID, MIXING WITH SOLVENT, CONTACTING SECOND MIXTURE WITH INSOLUBLIZATION AGENT TO PRODUCE ALUMINOXANE COMPOSITION, COMBINING WITH TRANSITION METAL CATALYST, POLYMERIZING OLEFIN | PHILLIPS PETROLEUM COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-0812860-B1 | Processes to produce organo-aluminoxane compositions | PHILLIPS PETROLEUM CO (US) | 2000-08-30 | — | — | EP | disclosed |
| US-6096915-A | Processes to produce organo-aluminoxane compositions | PALACKAL SYRIAC J (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0812860-A1 | Processes to produce organo-aluminoxane compositions | PHILLIPS PETROLEUM COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5480848-A | CONTAINING METALLOCENE AND REACTION PRODUCT OF ACIDIC HYDROGEN FREE ORGANIC BORANE AND ORGANOALUMINOXANE; ANTIFOULING, BROAD MOLECULAR WEIGHT DISTRIBUTION; POLYETTHYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5416179-A | Metallocene, isobutene | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5414180-A | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0634416-A1 | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0630900-A1 | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5354721-A | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1994-10-11 | — | — | US | disclosed |