Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 7/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 2/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212251 | 0.87 | GNAI3 (0.59) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL18092757 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL3706672 | 0.86 | — | — | |
| SCHEMBL6345121 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL11571907 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL7991671 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL18630997 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL1043420 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL1043024 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA | |
| SCHEMBL6566402 | 0.86 | GNAI3 (0.74) | GNAO1GNAI3GNAI1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37556-E1 | (ALKOXYPHENYL)THIAZOLE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |