Gilretinol Acetate

Gilretinol Acetate

SCHEMBL7705148

CC(=O)OC/C=C(\C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
MAPT P10636 7/20 1.00
CYP3A4 P08684 6/20 1.00
SLCO1B3 Q9NPD5 2/20 1.00
SLCO1B1 Q9Y6L6 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
HPGD P15428 1/20 1.00
ADORA3 P0DMS8 3/20 0.74
APP P05067 4/20 0.71
SNCA P37840 4/20 0.71
RBP4 P02753 4/20 0.71
MAPK1 P28482 3/20 0.71
ALOX15 P16050 3/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
TSHR P16473 2/20 0.71
NR1I2 O75469 1/20 0.71
USP2 O75604 1/20 0.71
PTGS1 P23219 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gilretinol Acetate SCHEMBL14204855 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL28272980 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL3332545 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL21588 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Zuretinol Acetate SCHEMBL1173917 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL1363443 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL21589 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL7021710 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL22636388 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1
Gilretinol Acetate SCHEMBL10928186 0.99 ALDH1A1 (0.98) ALDH1A1MAPTCYP3A4SLCO1B3SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114127273-A Novel beta-carotene oxidase 帝斯曼知识产权资产管理有限公司 2022-03-01 CN claimed
CN-111107832-A Production of retinyl esters 帝斯曼知识产权资产管理有限公司 2020-05-05 CN claimed
CN-111107834-A Biosynthesis of retinoids 帝斯曼知识产权资产管理有限公司 2020-05-05 CN claimed
CN-119699475-A Use of berberine alkaloid in preventing and/or treating intestinal diseases IRP健康股份有限公司 2025-03-28 CN disclosed
CN-118354768-A Novel compositions 帝斯曼知识产权资产管理有限公司 2024-07-16 CN disclosed
CN-118119700-A Retinoid production 帝斯曼知识产权资产管理有限公司 2024-05-31 CN disclosed
US-20220356503-A1 NOVEL BETA-CAROTENE OXIDASES DSM IP ASSETS B.V. (NL) 2022-11-10 US disclosed
EP-3999634-A1 NOVEL BETA-CAROTENE OXIDASES DSM IP Assets B.V. (NL) 2022-05-25 EP disclosed
CN-114127273-A Novel beta-carotene oxidase 帝斯曼知识产权资产管理有限公司 2022-03-01 CN disclosed
CN-107567493-B Bacillus strains for improving the health and performance of production animals 诺维信公司 2021-11-16 CN disclosed
WO-2021009194-A1 NOVEL BETA-CAROTENE OXIDASES DSM IP ASSETS B.V. (NL) 2021-01-21 WO disclosed
CN-111107834-A Biosynthesis of retinoids 帝斯曼知识产权资产管理有限公司 2020-05-05 CN disclosed
CN-111107832-A Production of retinyl esters 帝斯曼知识产权资产管理有限公司 2020-05-05 CN disclosed
CN-110709080-A Use of berberine alkaloid preparation in preventing and/or treating infectious diseases IRP健康股份有限公司 2020-01-17 CN disclosed
CN-110650739-A Use of berberine alkaloid in preventing and/or treating intestinal diseases IRP健康股份有限公司 2020-01-03 CN disclosed
CN-102976937-B For treating retinoid and the using method thereof of visual disorder 华盛顿大学 2016-12-21 CN disclosed
US-6348622-B1 CHEMICAL INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
US-6329414-B1 SYNTHETIC OR NATURALLY OCCURRING PHYTONUTRIENT OF CANTHANAXIN, LIMONENE AND/OR VITAMIN A; CYTOPROTECTIVE SELECTED FROM D- OR L-HISTIDINE, RACEMIC, NON-RACEMIC MIXTURE, NUTRICEUTICALLY INERT CARRIER, SUCH AS MICROCRYSTALLINE CELLULOSE CYTOS PHARMACEUTICALS LLC 2001-12-11 US disclosed
US-5972985-A CYTO-PROTECTIVE AGENT SELECTED FROM THE GROUP CONSISTING OF D-HISTIDINE, L-HISTIDINE, A RACEMIC MIXTURE THEREOF, A PHYTONUTRIENT HAVING ANTIOXIDANT ACTIVITY SELECTED FROM CAROTENOIDS, FLAVONOIDS, TOCOPHEROLS, ASCORBATES CYTOS PHARMACEUTICALS, LLC (US) 1999-10-26 US disclosed
EP-0900785-A2 Vitamin A related compounds and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-10 EP disclosed