Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96010 | 1.00 | SLC22A6 (0.42) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL27767112 | 1.00 | SLC22A6 (0.42) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL5182184 | 0.82 | GPR84 (0.44) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL7920481 | 0.80 | SLC22A6 (0.39) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL6257549 | 0.79 | GPR84 (0.50) | SLC22A6GPR84TDP1 | |
| SCHEMBL1895728 | 0.77 | SLC22A6 (0.48) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL3064786 | 0.77 | SLC22A6 (0.48) | SLC22A6SMN1; SMN2GPR84MAPTGABRR1 | |
| SCHEMBL1131427 | 0.76 | SLC22A6 (0.36) | SLC22A6SMN1; SMN2GPR84MAPTFFAR3 | |
| SCHEMBL10780889 | 0.76 | GPR84 (0.61) | SLC22A6GPR84MAPTTDP1 | |
| SCHEMBL10779087 | 0.76 | GPR84 (0.61) | SLC22A6GPR84MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472544-B1 | REACTING ACETIC ACID DERIVATIVE WITH AN ENOLATE, REDUCING WITH A MICROORGANISM, ACETALIZING IN PRESENCE OF ACID CATALYST THEN ALKALINE SAPONIFICATION; NO SPECIAL EQUIPMENT OR SUPER LOW TEMPERATURE REQUIRED; INEXPENSIVE STARTING MATERIALS | KANEKA CORPORATION (JP) | 2002-10-29 | — | — | US | disclosed |