Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.45 |
| ▸ | ITGAV | P06756 | 13/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853814 | 1.00 | ITGB3 (0.45) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL6859209 | 0.98 | ITGB3 (0.45) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL6859241 | 0.95 | ITGB3 (0.50) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL7711502 | 0.92 | ITGB3 (0.41) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL6854032 | 0.86 | ITGB3 (0.46) | ITGB3ITGAVITGA2BHTR1AHTR2A | |
| SCHEMBL6859265 | 0.84 | ITGB3 (0.46) | ITGB3ITGAVITGA2BHTR1AHTR2A | |
| SCHEMBL7713835 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL6860791 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL7708659 | 0.83 | ITGB3 (0.43) | ITGB3ITGAVITGA2BHTR1AHTR1D | |
| SCHEMBL6860274 | 0.83 | ITGB3 (0.43) | ITGB3ITGAVITGA2BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |