Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.93 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL30683809 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL331172 | 1.00 | — | — | |
| Styrene SCHEMBL30598432 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL7868857 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL7868854 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL770534 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL28101108 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL30763628 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL28225015 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1TP53MAOB | |
| Styrene SCHEMBL28190073 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1TP53MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981102-B | Prepare the method for expandable polystyrene | ARKEMA FRANCE (FR) | 2016-01-20 | — | — | CN | claimed |
| CN-101981102-A | Process for the preparation of expandable polystyrene | ARKEMA FRANCE | 2011-02-23 | — | — | CN | claimed |
| US-3940875-A | Method of treating soil for controlling termites and the like | BASILE MARIO J | 1976-03-02 | — | — | US | claimed |
| JP-8283571-A | — | — | None | — | — | JP | disclosed |
| JP-56051424-A | — | — | None | — | — | JP | disclosed |
| EP-3068576-B1 | FLUX FORMULATIONS | ALPHA ASSEMBLY SOLUTIONS INC (US) | 2025-10-01 | — | — | EP | disclosed |
| CN-119569526-A | Method for photosynthesizing o-dihalogenated compound based on non-corrosive inorganic halogen salt | 苏州大学 | 2025-03-07 | — | — | CN | disclosed |
| EP-2791979-B1 | PHOTOVOLTAIC CELL AND METHOD OF FORMING THE SAME | IMEC VZW (BE) | 2020-04-29 | — | — | EP | disclosed |
| EP-3037479-B1 | HALOGEN-FREE RESIN COMPOSITION AND USE THEREOF | SHENGYI TECHNOLOGY CO LTD (CN) | 2019-06-05 | — | — | EP | disclosed |
| US-9890276-B2 | Composite material, high-frequency circuit substrate made therefrom and making method thereof | GUANGDONG SHENGYI SCI. TECH CO., LTD (CN) | 2018-02-13 | — | — | US | disclosed |
| EP-2595460-B1 | COMPOSITE MATERIAL AND HIGH FREQUENCY CIRCUIT SUBSTRATE MANUFACTURED WITH THE COMPOSITE MATERIAL AND THE MANUFACTURING METHOD THEREOF | GUANGDONG SHENGYI SCI TECH CO (CN) | 2017-10-11 | — | — | EP | disclosed |
| US-4342607-A | CONTAINING A HALOGEN COMPOUND AS AN ACTIVATOR, AND A POLYCARBOXYLIC ACID OR A KETO ACID SURFACTANT | WESTERN ELECTRIC COMPANY, INC. (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0032062-A2 | High-molecular-weight novolak substituted phenolic resins and their preparation | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |
| JP-S5651424-A | PREPARATION OF NUCLEUS-BROMINATED STYRENE | TERADA AKIRA | 1981-05-09 | — | — | JP | disclosed |
| US-4264658-A | Three-component polymeric coating for glass substrate | OWENS-ILLINOIS, INC. (US) | 1981-04-28 | — | — | US | disclosed |
| US-4094756-A | Photochemical modification of polymers | OWENS-ILLINOIS, INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4086373-A | Protective polymeric coating for glass substrate | OWENS-ILLINOIS, INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4043073-A | Method of treating soil for controlling termites and the like | BASILE MARIO J | 1977-08-23 | — | — | US | disclosed |
| US-3941759-A | A QUINONE PHOTOSENSITIZER AND A TRANSITION METAL DIALKYL-DITHIOCARBAMATE | OWENS-ILLINOIS, INC. (US) | 1976-03-02 | — | — | US | disclosed |
| US-3940875-A | Method of treating soil for controlling termites and the like | BASILE MARIO J | 1976-03-02 | — | — | US | disclosed |