Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.87 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecylamine SCHEMBL7697638 | 1.00 | DNM1 (0.87) | DNM1TSHRTHRBALDH1A1LMNA | |
| Iodide SCHEMBL7698983 | 1.00 | DNM1 (0.87) | DNM1TSHRTHRBALDH1A1LMNA | |
| SCHEMBL31301121 | 0.97 | — | — | |
| Iodide SCHEMBL18662005 | 0.93 | — | — | |
| Dodecylamine SCHEMBL7697639 | 0.93 | DNM1 (0.87) | DNM1TSHRTHRBALDH1A1LMNA | |
| Iodide SCHEMBL18662004 | 0.93 | DNM1 (0.87) | DNM1TSHRTHRBALDH1A1LMNA | |
| Iodide SCHEMBL7705430 | 0.93 | DNM1 (0.87) | DNM1TSHRTHRBALDH1A1LMNA | |
| Iodide SCHEMBL20593889 | 0.93 | — | — | |
| Tetradecylamine SCHEMBL11856039 | 0.90 | DNM1 (0.93) | DNM1TSHRTHRBALDH1A1LMNA | |
| Dodecylamine SCHEMBL7359047 | 0.90 | DNM1 (0.93) | DNM1TSHRTHRBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344662-B1 | Thin-film field-effect transistor with organic-inorganic hybrid semiconductor requiring low operating voltages | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2002-02-05 | — | — | US | claimed |
| US-6344662-B1 | Thin-film field-effect transistor with organic-inorganic hybrid semiconductor requiring low operating voltages | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2002-02-05 | — | — | US | disclosed |