Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4914365 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL31498258 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6458542 | 0.75 | — | — | |
| SCHEMBL7641186 | 0.74 | NPC1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6467747 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL30166966 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL716165 | 0.69 | — | — | |
| SCHEMBL2863177 | 0.69 | NPC1 (0.37) | — | |
| Toluene SCHEMBL28102048 | 0.69 | NPC1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7709400 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448349-B1 | STEREORIGID METALLOCENE FOR BLOCK GAS PHASE POLYMERIZING OLEFINS HAVING THREE OR MORE CARBON ATOMS | FINA RESEARCH, S.A. (BE) | 2002-09-10 | — | — | US | disclosed |
| US-6348272-B1 | Polyolefins and uses thereof | FINA RESEARCH, S.A. (BE) | 2002-02-19 | — | — | US | disclosed |
| EP-0910591-B1 | SYNDIOTACTIC/ATACTIC BLOCK POLYOLEFINS, CATALYSTS AND PROCESSES FOR PRODUCING THE SAME | FINA RESEARCH (BE) | 2001-03-21 | — | — | EP | disclosed |
| EP-0931814-A1 | Polyolefins and uses thereof | FINA RESEARCH S.A. (BE) | 1999-07-28 | — | — | EP | disclosed |
| EP-0818475-A1 | Syndiotactic/atactic block polyolefins, catalysts and processes for producing the same | FINA RESEARCH S.A. (BE) | 1998-01-14 | — | — | EP | disclosed |