Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404708 | 0.76 | PTPN1 (0.41) | PTPN1CYP19A1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29421727 | 0.76 | PTPN1 (0.41) | PTPN1CYP19A1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29552568 | 0.76 | PTPN1 (0.41) | PTPN1CYP19A1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29366469 | 0.76 | PTPN1 (0.41) | PTPN1CYP19A1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29379465 | 0.76 | PTPN1 (0.40) | PTPN1CYP19A1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29397485 | 0.75 | PTPN1 (0.44) | PTPN1CYP19A1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3494203 | 0.69 | PTPN1 (0.47) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL13401501 | 0.69 | PTPN1 (0.47) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL31676710 | 0.69 | PTPN1 (0.45) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL2398561 | 0.69 | PTPN1 (0.47) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359000-B1 | PINE ROOT (DEUTERO MYCETES) FUNGAL METABOLITE, NATURALLY OCCURRING TERPENOID, STEROID, AND POLYKETIDE COMPOUNDS, | MILLENNIUM PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |
| US-6060509-A | ADMINISTERING DOSAGE OF TERPENOID PLANT EXTRACT TO TREAT FUNGAL INFECTION IN MAMMAL | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2000-05-09 | — | — | US | disclosed |
| US-5932613-A | PINE ROOT FUNGAL METABOLITE OR ANALOG | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1999-08-03 | — | — | US | disclosed |
| US-5917084-A | PINE ROOT (DEUTERO MYCETES) FUNGAL METABOLITE, NATURALLY OCCURRING TERPENOID COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| WO-1998000121-A1 | ANTICANCER AGENTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| WO-1998000091-A2 | ANTIFUNGAL AGENTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | disclosed |