Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494203 | 1.00 | PTPN1 (0.47) | PTPN1HSD11B1HSD11B2PLA2G2AIDO1 | |
| SCHEMBL2398561 | 1.00 | PTPN1 (0.47) | PTPN1HSD11B1HSD11B2PLA2G2AIDO1 | |
| SCHEMBL2037733 | 0.88 | PTPN1 (0.47) | PTPN1HSD11B1HSD11B2F10MEN1 | |
| SCHEMBL28653806 | 0.84 | PTPN1 (0.37) | PTPN1HSD11B1HSD11B2NR1H4 | |
| SCHEMBL2396305 | 0.82 | PTPN1 (0.49) | PTPN1HSD11B1HSD11B2IDO1ALDH1A1 | |
| SCHEMBL30387208 | 0.81 | PTPN1 (0.52) | PTPN1HSD11B1HSD11B2CYP2C9F10 | |
| SCHEMBL29421727 | 0.80 | PTPN1 (0.41) | PTPN1HSD11B1HSD11B2IDO1ALDH1A1 | |
| SCHEMBL29552568 | 0.80 | PTPN1 (0.41) | PTPN1HSD11B1HSD11B2IDO1ALDH1A1 | |
| SCHEMBL29366469 | 0.80 | PTPN1 (0.41) | PTPN1HSD11B1HSD11B2IDO1ALDH1A1 | |
| SCHEMBL29404708 | 0.80 | PTPN1 (0.41) | PTPN1HSD11B1HSD11B2IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | SORD, CASP3, TXNRD2 | PTPN1 3492/4885HSD11B1 187/4885HSD11B2 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.