Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL308226 | 1.00 | — | — | |
| Bicarbonate SCHEMBL87276 | 1.00 | — | — | |
| Bicarbonate SCHEMBL294626 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL10386542 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL10904150 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL3995099 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5836395 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8000370 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL21796220 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8209384 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118006088-A | Ultra-high fluidity polyester elastomer material, and preparation method and application method thereof | 上海普利特复合材料股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-107343466-A | A kind of degradable fertilizer apparatus for acting on trees ' root | 许家瑜 | 2017-11-14 | — | — | CN | claimed |
| CN-106566497-A | Controllable organic blocking agent for oil and gas fields and preparation method of controllable organic blocking agent | 青海华鑫石油材料有限责任公司 | 2017-04-19 | — | — | CN | claimed |
| CN-105968876-A | Compound type reactive dye formula | 叶文佳 | 2016-09-28 | — | — | CN | claimed |
| CN-105238602-A | Degreasing agent and preparation method therefor | CHONGQING HUANYAN SCIENCE AND TECHNOLOGY ENVIRONMENTAL CO LTD | 2016-01-13 | — | — | CN | claimed |
| CN-105039008-A | Chamomile flavor laundry detergent | YANG BIN | 2015-11-11 | — | — | CN | claimed |
| CN-102106590-A | Sleeve-fish inflation agent and using method thereof | GREAT SOUTHERN THROUGH THE DEV OF BIOTECHNOLOGY | 2011-06-29 | — | — | CN | claimed |
| CN-118006088-A | Ultra-high fluidity polyester elastomer material, and preparation method and application method thereof | 上海普利特复合材料股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-106830999-B | Precious metal preparation resistant to dish washing machine | 深圳市瑞琼科技材料有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-106830999-A | A kind of noble metal preparation of resistance to dish-washing machine | 深圳市瑞琼科技材料有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106566497-A | Controllable organic blocking agent for oil and gas fields and preparation method of controllable organic blocking agent | 青海华鑫石油材料有限责任公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-105968876-A | Compound type reactive dye formula | 叶文佳 | 2016-09-28 | — | — | CN | disclosed |
| CN-105603776-A | Formula of reactive dye | WUXI CHANG'AN SHUGUANG GLOVES FACTORY | 2016-05-25 | — | — | CN | disclosed |
| CN-105238602-A | Degreasing agent and preparation method therefor | CHONGQING HUANYAN SCIENCE AND TECHNOLOGY ENVIRONMENTAL CO LTD | 2016-01-13 | — | — | CN | disclosed |
| CN-105039008-A | Chamomile flavor laundry detergent | YANG BIN | 2015-11-11 | — | — | CN | disclosed |
| CN-102106590-A | Sleeve-fish inflation agent and using method thereof | GREAT SOUTHERN THROUGH THE DEV OF BIOTECHNOLOGY | 2011-06-29 | — | — | CN | disclosed |
| JP-2002338985-A | HOT-WORKING POWDER LUBRICANT COMPOSITION | SUMITOMO METAL IND LTD | 2002-11-27 | — | — | JP | disclosed |