Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917685 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL6907975 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL16321856 | 0.88 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL15535996 | 0.86 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL9542135 | 0.85 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL9642466 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL23536155 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL16979039 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL17609123 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL9643779 | 0.80 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3FFAR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900218-B1 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0900218-A4 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2001-05-23 | — | — | EP | disclosed |
| US-6117883-A | Heterocyclic compounds | ELI LILLY AND COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0900218-A1 | HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| CN-1041268-C | Method of controlling insects and acarids | FMC CORP (US) | 1998-12-23 | — | — | CN | disclosed |
| WO-1997040044-A1 | HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-10-30 | — | — | WO | disclosed |
| CN-1029123-C | Process for preparation of insecticidal cyclopropyl-substituted di(aryl) compounds | FMC CORP (US) | 1995-06-28 | — | — | CN | disclosed |
| CN-1069962-A | The preparation method of parasiticidal cyclopropyl-replacement two (aromatic base) compound | FMC CORP (US) | 1993-03-17 | — | — | CN | disclosed |
| CN-1020091-C | Cyclopropyl-substituted di (aryl) insecticidal compositions | FMC CORP (US) | 1993-03-17 | — | — | CN | disclosed |
| CN-1069168-A | Method for controlling insects and acarids | FMC CORP (US) | 1993-02-24 | — | — | CN | disclosed |
| EP-0357610-B1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC Corporation (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0357610-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS. | FMC CORP (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4808762-A | Insecticidal cyclopropyl-substituted di(aryl) compounds | FMC CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| WO-1988008416-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |
| CN-88101892-A | insecticidal cyclopropyl-substituted di (aryl) compounds | — | 1988-11-02 | — | — | CN | disclosed |