SCHEMBL7705776

SCHEMBL7705776

Cc1ccc(S(=O)(=O)OCCCCCCCCCCCSCCCCC(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 3/20 0.44
STAT3 P40763 1/20 0.41
TBXAS1 P24557 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PSMD10 O75832 1/20 0.40
LTB4R Q15722 1/20 0.40
TSHR P16473 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 1/20 0.39
G6PD P11413 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10449020 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL9764712 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL8864017 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL8863706 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL17614843 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL25030574 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL9458218 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL7827739 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL30850377 0.93 STAT3 (0.46) STAT3TBXAS1L3MBTL1PSMD10LTB4R
SCHEMBL6238329 0.92 STAT3 (0.47) STAT3TBXAS1L3MBTL1PSMD10LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362352-B1 MEDICAL DIAGNOSIS DUKE UNIVERSITY 2002-03-26 US disclosed