Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19629759 | 1.00 | GPR84 (0.39) | GPR84FFAR1FFAR4L3MBTL1PSMD14 | |
| SCHEMBL30787428 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL30787116 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL2845646 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL30787207 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL23530055 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL30787307 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL14660129 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL30787291 | 0.87 | GPR84 (0.46) | GPR84FFAR1FFAR4PSMD14PLA2G1B | |
| SCHEMBL28581845 | 0.84 | FFAR4 (0.38) | GPR84FFAR1FFAR4L3MBTL1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362352-B1 | MEDICAL DIAGNOSIS | DUKE UNIVERSITY | 2002-03-26 | — | — | US | disclosed |
| WO-2000063216-A1 | F-18-LABELED THIA FATTY ACIDS AND METHODS OF MAKING AND USING THE SAME | DUKE UNIVERSITY (US) | 2000-10-26 | — | — | WO | disclosed |