Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHAT | P28329 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805082 | 0.78 | CHAT (0.54) | KDM4EMEN1MAPTKMT2AENPP2 | |
| SCHEMBL10846493 | 0.76 | KDM4E (0.64) | KDM4EMEN1MAPTKMT2AENPP2 | |
| SCHEMBL3144474 | 0.76 | KDM4E (0.64) | KDM4EMEN1MAPTKMT2AENPP2 | |
| Cinnamonitrile SCHEMBL996307 | 0.72 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2AENPP2 | |
| Cinnamonitrile SCHEMBL23933 | 0.72 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2AENPP2 | |
| Cinnamonitrile SCHEMBL23599 | 0.72 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2AENPP2 | |
| SCHEMBL11125760 | 0.72 | KDM4E (0.59) | KDM4EMEN1MAPTKMT2AENPP2 | |
| SCHEMBL5186155 | 0.70 | KDM4E (0.52) | KDM4EENPP2FDPSESR1 | |
| SCHEMBL5186158 | 0.70 | KDM4E (0.52) | KDM4EENPP2FDPSESR1 | |
| SCHEMBL2986380 | 0.68 | KDM4E (0.55) | KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |