Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160977 | 1.00 | KDM4E (0.55) | KDM4ENFE2L2HSD11B1APPPTGS1 | |
| SCHEMBL2986381 | 1.00 | KDM4E (0.55) | KDM4ENFE2L2HSD11B1APPPTGS1 | |
| SCHEMBL18160982 | 1.00 | KDM4E (0.55) | KDM4ENFE2L2HSD11B1APPPTGS1 | |
| SCHEMBL22065499 | 1.00 | KDM4E (0.55) | KDM4ENFE2L2HSD11B1APPPTGS1 | |
| SCHEMBL9107907 | 0.88 | NFE2L2 (0.48) | KDM4ENFE2L2HSD11B1PTGS1ALDH1A1 | |
| SCHEMBL9107905 | 0.88 | NFE2L2 (0.48) | KDM4ENFE2L2HSD11B1PTGS1ALDH1A1 | |
| Pyridine SCHEMBL27556477 | 0.85 | NFE2L2 (0.47) | KDM4ENFE2L2HSD11B1ALDH1A1MAPT | |
| SCHEMBL10846493 | 0.85 | KDM4E (0.64) | KDM4ENFE2L2FBP1ALDH1A1MAPT | |
| SCHEMBL3144474 | 0.85 | KDM4E (0.64) | KDM4ENFE2L2FBP1ALDH1A1MAPT | |
| SCHEMBL11125760 | 0.80 | KDM4E (0.59) | KDM4EFBP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708027-A | Method for preparing boronated carbonyl derivative | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-112064165-B | Antistatic textile fabric and preparation method thereof | 昱天(上海)新材料有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-112064165-A | Antistatic textile fabric and preparation method thereof | 满遵连 | 2020-12-11 | — | — | CN | claimed |
| CN-112058096-A | Nanofiltration membrane and preparation method thereof | 朱荣艳 | 2020-12-11 | — | — | CN | claimed |
| EP-1140832-A4 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS INC (US) | 2004-11-03 | — | — | EP | claimed |
| WO-2002076940-A2 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | claimed |
| US-20010053862-A1 | Process for preparing arylpiperidine carbinol intermediates and derivatives | PENTECH PHARMACEUTICALS, INC. | 2001-12-20 | — | — | US | claimed |
| EP-1140832-A1 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037443-A1 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2000-06-29 | — | — | WO | claimed |
| CN-116135861-A | Method for preparing boronated carbonyl derivative from alpha, beta-unsaturated carbonyl derivative | 中国科学院大连化学物理研究所 | 2023-05-19 | — | — | CN | disclosed |
| EP-3625218-B1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3625218-B1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| CN-114437085-A | Preparation method of Ruicapa intermediate | 烟台弘邦医药科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3553097-B1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| WO-2001017999-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| WO-2000037443-A1 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2000-06-29 | — | — | WO | disclosed |
| WO-2000026187-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | SYNTHON B.V. (NL) | 2000-05-11 | — | — | WO | disclosed |
| US-4705807-A | NERVOUS SYSTEM DISORDERS | LILLY INDUSTRIES LIMITED (GB) | 1987-11-10 | — | — | US | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4012377-A | ANTIMICROBIAL, PARASITICIDES | GLAXO LABORATORIES LIMITED (EN) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053862-A1 | Process for preparing arylpiperidine carbinol intermediates and derivatives | ADH1C, CBR1, MAL2 | KDM4E 1948/4885NFE2L2 385/4885HSD11B1 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.