Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.44 |
| ▸ | HMGCR | P04035 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ECE1 | P42892 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705797 | 0.81 | FFAR1 (0.53) | CYSLTR2CYSLTR1PTPN7HMGCRMAPT | |
| SCHEMBL8352544 | 0.79 | FFAR1 (0.57) | PTPN7HMGCRMAPTRXFP1HDAC3 | |
| SCHEMBL10592931 | 0.79 | FFAR1 (0.57) | PTPN7HMGCRMAPTRXFP1HDAC3 | |
| SCHEMBL10795247 | 0.79 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1PTPN7HMGCRMAPT | |
| SCHEMBL7705813 | 0.78 | FFAR1 (0.55) | CYSLTR2CYSLTR1PTPN7HMGCRMAPT | |
| SCHEMBL7680525 | 0.78 | KCNH2 (0.50) | CYSLTR2CYSLTR1HCAR2MAPTKDM4E | |
| SCHEMBL7683468 | 0.78 | KCNH2 (0.50) | CYSLTR2CYSLTR1HCAR2MAPTKDM4E | |
| SCHEMBL14007856 | 0.77 | FFAR1 (0.57) | PTPN7HMGCRMAPTRXFP1HDAC3 | |
| SCHEMBL15022608 | 0.77 | KDM4E (0.57) | HCAR2MAPTMMEECE1KDM4E | |
| SCHEMBL27809224 | 0.76 | FFAR1 (0.56) | PTPN7HMGCRMAPTRXFP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355490-B1 | CODING INDIVIDUAL MEMBERS OF LIBRARY; COVALENTLY BONDING NITRILE TO SOLID SUPPORT; DETECTION BY INFRARED OR RAMAN SPECTROSCOPY | ABBOTT LABORATORIES | 2002-03-12 | — | — | US | disclosed |
| US-6274385-B1 | COVALENTLY ATTACHING TO EACH SOLID SUPPORT AT LEAST ONE ACETYLENE CODING IDENTIFIER DETECTABLE BY INFRARED OR RAMAN SPECTROSCOPY TO CODE INDIVIDUAL MEMBERS OF A COMBINATORIAL CHEMICAL LIBRARY | ABBOTT LABORATORIES | 2001-08-14 | — | — | US | disclosed |
| EP-0879219-B1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | ABBOTT LAB (US) | 2000-03-01 | — | — | EP | disclosed |
| EP-0879219-A1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | Abbott Laboratories (US) | 1998-11-25 | — | — | EP | disclosed |
| WO-1998011036-A9 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | — | 1998-07-09 | — | — | WO | disclosed |
| WO-1998011036-A1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | ABBOTT LABORATORIES (US) | 1998-03-19 | — | — | WO | disclosed |