Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 19/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352093 | 0.83 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7219810 | 0.81 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL6343888 | 0.78 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL7220676 | 0.71 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL7565036 | 0.70 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7214245 | 0.70 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7220849 | 0.68 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5419526 | 0.67 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL6779041 | 0.66 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL7029271 | 0.66 | CRHR1 (0.44) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352990-B1 | A METHOD OF TREATING ANXIETY AND DEPRESSION IN A WARM-BLOODED ANIMAL AND TREATMENT OF STROKES | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-05 | — | — | US | disclosed |