Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819944 | 0.81 | CES1 (0.50) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL9618568 | 0.80 | CES1 (0.77) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL16158157 | 0.80 | CES1 (0.56) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL17080312 | 0.78 | CES1 (0.58) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL28993094 | 0.78 | CES1 (0.53) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL16626105 | 0.78 | CES1 (0.53) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL6203510 | 0.77 | CES1 (0.56) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL11819939 | 0.75 | CES1 (0.50) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL12260648 | 0.75 | CES1 (0.58) | CES1CES2CA1CA2ALDH1A1 | |
| SCHEMBL8824303 | 0.73 | CA1 (0.67) | CES1CES2CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020068275-A1 | METHODS OF USING A CHIMERIC NUCLEIC ACID/NUCLEIC ACID ANALOGUE MOLECULE | AMERSHAM INTERNATIONAL PLC (GB) | 2002-06-06 | — | — | US | disclosed |
| EP-0720615-B1 | ELONGATION, AMPLIFICATION AND SEQUENCE DETERMINATION USING A CHIMERIC OLIGONUCLEOTIDE | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2000-07-26 | — | — | EP | disclosed |
| EP-0720615-A1 | REAGENTS COMPRISING CHIMERIC MOLECULES OF NUCLEIC ACIDS AND NUCLEIC ACID ANALOGS | AMERSHAM INTERNATIONAL plc (GB) | 1996-07-10 | — | — | EP | disclosed |
| EP-0215942-B1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | ANTIVIRALS INC (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1995008556-A1 | REAGENTS COMPRISING CHIMERIC MOLECULES OF NUCLEIC ACIDS AND NUCLEIC ACID ANALOGS | AMERSHAM INTERNATIONAL PLC (GB) | 1995-03-30 | — | — | WO | disclosed |
| EP-0639582-A2 | Polynucleotide assay reagent and method | ANTIVIRALS INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5217866-A | Polynucleotide assay reagent and method | ANTI-GENE DEVELOPMENT GROUP (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0216860-B1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON, James (US) | 1992-10-28 | — | — | EP | disclosed |
| EP-0216860-A4 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0216860-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005518-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |