Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203510 | 0.85 | CES1 (0.56) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL6045338 | 0.84 | KCNN4 (0.55) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL15519395 | 0.83 | CES1 (0.56) | CES1CES2KCNN4CA1CA2 | |
| SCHEMBL1508202 | 0.83 | CES1 (0.56) | CES1CES2KCNN4CA1CA2 | |
| SCHEMBL12260648 | 0.83 | CES1 (0.58) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL2316036 | 0.82 | KCNN4 (0.53) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL16147101 | 0.81 | CES1 (0.56) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL9850356 | 0.80 | CES1 (0.54) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL28993094 | 0.79 | CES1 (0.53) | CES1CES2NPC1RAB9APTGS2 | |
| SCHEMBL10603215 | 0.78 | KCNN4 (0.49) | CES1CES2NPC1RAB9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114480401-B | Clofarabine modified oligonucleotide | 湖南大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-114480401-A | Clofarabine modified oligonucleotide | 湖南大学 | 2022-05-13 | — | — | CN | disclosed |
| WO-2015138868-A9 | TRANS-ACTING ELEMENTS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID SEQUENCES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2015-11-19 | — | — | WO | disclosed |
| WO-2015138868-A1 | TRANS-ACTING ELEMENTS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID SEQUENCES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2015-09-17 | — | — | WO | disclosed |