⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703184 | 0.75 | — | — | |
| SCHEMBL506522 | 0.73 | — | — | |
| SCHEMBL9174402 | 0.62 | TSHR (0.32) | — | |
| SCHEMBL505793 | 0.61 | — | — | |
| SCHEMBL151 | 0.58 | — | — | |
| SCHEMBL29129477 | 0.58 | TSHR (0.31) | — | |
| SCHEMBL10524658 | 0.58 | — | — | |
| SCHEMBL2510885 | 0.58 | NR1H2 (0.33) | — | |
| SCHEMBL12482704 | 0.56 | — | — | |
| SCHEMBL17960006 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208234-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6348583-B1 | NUCLEOBASE CONTAINING POLYTHIOETHERS SYNTHESIZED ON POLYETHYLENE GLYCOL, SUCCINIC ANHYDRIDE AND PROPYLAMINE MODIFIED GLASS; NUCLEIC ACID MIMETICS | BIO-RAD LABORATORIES, INC. | 2002-02-19 | — | — | US | disclosed |
| WO-2001016365-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2001-03-08 | — | — | WO | disclosed |