SCHEMBL506522

SCHEMBL506522

CC(C)(C)[Si](C)(C)CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2510885 0.82 NR1H2 (0.33)
SCHEMBL10431571 0.78 LMNA (0.38)
SCHEMBL10439105 0.78 LMNA (0.38)
SCHEMBL505793 0.75
SCHEMBL1376695 0.73
SCHEMBL7703184 0.73
SCHEMBL7705966 0.73
SCHEMBL13437897 0.71
SCHEMBL8719522 0.71
SCHEMBL7810056 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102197055-A Curable composition for transfer material and pattern formation method SHOWA DENKO KK 2011-09-21 CN claimed
US-20110206834-A1 CURABLE COMPOSITION FOR TRANSFER MATERIALS, AND PATTERN FORMING PROCESS SHOWA DENKO K.K. (JP) 2011-08-25 US claimed
EP-2345676-A1 CURABLE COMPOSITION FOR TRANSFER MATERIAL AND PATTERN FORMATION METHOD SHOWA DENKO K.K. (JP) 2011-07-20 EP claimed
CN-111777626-B Venetian-dihydroartemisinin split compound and preparation and application thereof 沈阳药科大学 2021-07-09 CN disclosed
US-10640526-B2 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-05-05 US disclosed
US-20180319833-A1 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-11-08 US disclosed
EP-3377508-A1 METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE Centre National De La Recherche Scientifique (FR) 2018-09-26 EP disclosed
EP-3170832-A1 METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE Centre National De La Recherche Scientifique (FR) 2017-05-24 EP disclosed
CN-102388014-A Synthesis method of chiral alpha-aryl propionic acid derivative DSM IP ASSETS BV 2012-03-21 CN disclosed
US-20120029226-A1 METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES DSM IP ASSETS B.V. (NL) 2012-02-02 US disclosed
CN-102197055-A Curable composition for transfer material and pattern formation method SHOWA DENKO KK 2011-09-21 CN disclosed
US-5652368-A NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-07-29 US disclosed
US-5620978-A 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/NMDA receptor STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1997-04-15 US disclosed
WO-1996040141-A1 4,5-BRIDGED QUINOXALINEDIONES AND QUINOLONES AND THE USE THEREOF AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-5567830-A Process for synthesis of acetylenic carbinols COCENSYS, INC. (US) 1996-10-22 US disclosed
WO-1996022990-A2 AZA AND AZA (N-OXY) ANALOGS OF GLYCINE/NMDA RECEPTOR ANTAGONISTS STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and onbehalf of THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE, OREGON (US) 1996-08-01 WO disclosed
EP-0706396-A1 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE-3 OR 4-OXIMES AND USE STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) 1996-04-17 EP disclosed
US-5475007-A Preventing convulsions THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-12-12 US disclosed
WO-1995005378-A1 ANTIVIRAL THIAZOLES PFIZER INC. (US) 1995-02-23 WO disclosed
WO-1994027605-A1 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE-3 OR 4-OXIMES AND USE STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE, OREGON (US) 1994-12-08 WO disclosed