SCHEMBL7706356

SCHEMBL7706356

O=C1CCCCCCCC1C1CCCCCCCC1=O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
MT-CO2 P00403 6/20 0.49
ALOX5 P09917 6/20 0.49
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MCL1 Q07820 1/20 0.38
CA6 P23280 1/20 0.37
MAPT P10636 1/20 0.36
TLR4 O00206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6769544 1.00 KMT2A (0.56) KMT2ACA1CA2CA4MT-CO2
SCHEMBL6764761 1.00 KMT2A (0.56) KMT2ACA1CA2CA4MT-CO2
SCHEMBL535670 0.97 CA1 (0.55) KMT2ACA1CA2CA4MT-CO2
SCHEMBL2982970 0.94 CA1 (0.52) KMT2ACA1CA2CA4MT-CO2
Ethylene SCHEMBL6750614 0.92 CA1 (0.50) KMT2ACA1CA2CA4MT-CO2
SCHEMBL6535460 0.88 MT-CO2 (0.46) KMT2ACA1CA2CA4MT-CO2
SCHEMBL3277309 0.88 CA1 (0.43) KMT2ACA1CA2CA4MT-CO2
SCHEMBL10719777 0.88 MT-CO2 (0.46) KMT2ACA1CA2CA4MT-CO2
SCHEMBL4374227 0.88 MT-CO2 (0.46) KMT2ACA1CA2CA4MT-CO2
SCHEMBL3721835 0.87 KMT2A (0.50) KMT2ACA1CA2CA4MT-CO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0921125-B1 1,3,8-Triazaspiro[4,5]decan-4-on derivatives HOFFMANN LA ROCHE (CH) 2002-01-30 EP disclosed
US-6045968-A COMPRISING AN ACID-DECOMPOSABLE NOVOLAK RESIN, AN ALKALI-SOLUBLE RESIN AND A PHOTO-ACID GENERATING AGENT; HIGH ALKALI SOLUBILITY, HIGH RESOLUTION, AND HIGH REPRODUCIBILITY KABUSHIKI KAISHA TOSHIBA (JP) 2000-04-04 US disclosed
US-6043366-A USEFUL IN TREATING DISORDERS INVOLVING THE ORPHANIN FQ(A SEVENTEEN AMINO ACID LONG PEPTIDE) RECEPTOR. HOFFMAN-LA ROCHE INC. (US) 2000-03-28 US disclosed
EP-0921125-A1 1,3,8-Triaza-spiro 4,5 decan-4-on derivatives F. HOFFMANN-LA ROCHE AG (CH) 1999-06-09 EP disclosed
US-5837419-A ACID DECOMPOSABLE RESIN, PHOTO-ACID GENERATING AGENT AND NAPHTHOL NOVOLAK KABUSHIKI KAISHA TOSHIBA (JP) 1998-11-17 US disclosed