Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911368 | 0.88 | CYP1A2 (0.55) | CYP1A2LMNAMAPK1RECQLALDH1A1 | |
| SCHEMBL23875141 | 0.81 | CYP1A2 (0.57) | CYP1A2LMNAMAPK1RECQLALDH1A1 | |
| SCHEMBL10339386 | 0.80 | KDM4E (0.49) | CYP1A2LMNAMAPK1RECQLALDH1A1 | |
| SCHEMBL15807121 | 0.80 | RECQL (0.76) | CYP1A2RECQLALDH1A1HTTTP53 | |
| SCHEMBL10948671 | 0.77 | MAPT (0.47) | CYP1A2LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL16199705 | 0.76 | RECQL (0.54) | CYP1A2RECQLALDH1A1HTTTP53 | |
| SCHEMBL1681530 | 0.76 | RECQL (0.54) | CYP1A2MAPK1RECQLALDH1A1HTT | |
| SCHEMBL1681608 | 0.76 | RECQL (0.54) | CYP1A2RECQLALDH1A1HTTTP53 | |
| SCHEMBL10986775 | 0.75 | MAPT (0.59) | CYP1A2LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL11226340 | 0.74 | TSHR (0.46) | CYP1A2LMNAMAPK1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |