Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706419 | 0.88 | CYP1A2 (0.57) | CYP1A2LMNAMAPK1RECQLALDH1A1 | |
| SCHEMBL259219 | 0.79 | RECQL (0.73) | CYP1A2RECQLALDH1A1HTTKDM4E | |
| SCHEMBL23875141 | 0.79 | CYP1A2 (0.57) | CYP1A2LMNAMAPK1RECQLALDH1A1 | |
| SCHEMBL10339386 | 0.78 | KDM4E (0.49) | CYP1A2LMNAMAPK1RECQLALDH1A1 | |
| SCHEMBL10908262 | 0.76 | RECQL (0.54) | CYP1A2MAPK1RECQLALDH1A1HTT | |
| SCHEMBL9144912 | 0.75 | RECQL (0.53) | CYP1A2RECQLALDH1A1HTTKDM4E | |
| SCHEMBL10948671 | 0.75 | MAPT (0.47) | CYP1A2LMNAMAPK1ALDH1A1CRHR1 | |
| SCHEMBL10986775 | 0.72 | MAPT (0.59) | CYP1A2LMNAMAPK1ALDH1A1CRHR1 | |
| Trapidil SCHEMBL19438921 | 0.71 | MAPK1 (1.00) | CYP1A2LMNAMAPK1ALDH1A1HTT | |
| Trapidil SCHEMBL33563 | 0.71 | MAPK1 (1.00) | CYP1A2LMNAMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0101517-B1 | NOVEL S-TRIAZOLE(1,5-A)PYRIMIDINE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0101517-A1 | NOVEL s-TRIAZOLE(1,5-a)PYRIMIDINE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-29 | — | — | EP | disclosed |