Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7706367 | 0.99 | OPRL1 (0.56) | OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL14013754 | 0.89 | OPRL1 (0.61) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7705553 | 0.85 | OPRL1 (0.60) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7709410 | 0.84 | OPRL1 (0.67) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7701383 | 0.84 | OPRL1 (0.67) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7709456 | 0.83 | OPRL1 (0.64) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7706974 | 0.83 | OPRL1 (0.65) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7706449 | 0.83 | OPRL1 (0.65) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7706292 | 0.82 | OPRL1 (0.62) | OPRL1OPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7706375 | 0.82 | BDKRB2 (0.54) | OPRL1OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921125-B1 | 1,3,8-Triazaspiro[4,5]decan-4-on derivatives | HOFFMANN LA ROCHE (CH) | 2002-01-30 | — | — | EP | claimed |
| US-6043366-A | USEFUL IN TREATING DISORDERS INVOLVING THE ORPHANIN FQ(A SEVENTEEN AMINO ACID LONG PEPTIDE) RECEPTOR. | HOFFMAN-LA ROCHE INC. (US) | 2000-03-28 | — | — | US | claimed |