SCHEMBL7706714

SCHEMBL7706714

Nc1ccc2cccc3c2c1C(=O)OC3=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 6/20 0.62
ADORA2A P29274 3/20 0.42
CSNK1A1 P48729 2/20 0.42
CSNK1D P48730 2/20 0.42
CSNK1G1 Q9HCP0 2/20 0.42
FGR P09769 1/20 0.42
PIM1 P11309 1/20 0.42
MAOA P21397 1/20 0.42
DYRK1A Q13627 1/20 0.42
HIPK2 Q9H2X6 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MCL1 Q07820 2/20 0.41
CES2 O00748 1/20 0.41
BCHE P06276 1/20 0.41
CES1 P23141 1/20 0.41
ALOX15 P16050 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30568054 1.00 TYMS (0.62) TYMSADORA2ACSNK1A1CSNK1DCSNK1G1
SCHEMBL7750777 0.79 TYMS (0.62) TYMSMAOAALDH1A1MCL1CES2
SCHEMBL29937612 0.79 TYMS (0.62) TYMSALDH1A1MCL1CES2BCHE
SCHEMBL4960179 0.79 TYMS (0.62) TYMSALDH1A1MCL1CES2BCHE
SCHEMBL6289874 0.79 TYMS (0.62) TYMSALDH1A1MCL1CES2BCHE
SCHEMBL4958874 0.79 TYMS (0.62) TYMSADORA2AALDH1A1MCL1CES2
SCHEMBL4960210 0.79 TYMS (0.62) TYMSALDH1A1MCL1CES2BCHE
SCHEMBL322393 0.79 TYMS (0.62) TYMSALDH1A1MCL1CES2BCHE
SCHEMBL22580735 0.79 TYMS (0.62) TYMSALDH1A1MCL1CES2BCHE
1,8-Naphthalic Anhydride SCHEMBL30415 0.78 TYMS (1.00) TYMSALDH1A1MCL1CES2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109675525-A A kind of application of preparation and its absorption and separation methylene blue of metal supermolecular organogel 西北师范大学 2019-04-26 CN claimed
CN-109294558-A Subjective and Objective assembling supermolecular gel and its preparation and application based on pyromellitic trimethylsilyl chloride functionalization 西北师范大学 2019-02-01 CN claimed
CN-110302760-A A kind of amino-carbon hydroxyapatite composite material and its preparation method and application 衡阳师范学院 2019-10-08 CN disclosed
CN-109675525-A A kind of application of preparation and its absorption and separation methylene blue of metal supermolecular organogel 西北师范大学 2019-04-26 CN disclosed
CN-109675525-A A kind of application of preparation and its absorption and separation methylene blue of metal supermolecular organogel 西北师范大学 2019-04-26 CN disclosed
CN-109294558-A Subjective and Objective assembling supermolecular gel and its preparation and application based on pyromellitic trimethylsilyl chloride functionalization 西北师范大学 2019-02-01 CN disclosed
CN-109294558-A Subjective and Objective assembling supermolecular gel and its preparation and application based on pyromellitic trimethylsilyl chloride functionalization 西北师范大学 2019-02-01 CN disclosed
CN-109293619-A 4- dimethylamino -1,8- naphthalic anhydride and the preparation method and application thereof 华南师范大学 2019-02-01 CN disclosed
US-6362181-B1 BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS WARNER-LAMBERT COMPANY 2002-03-26 US disclosed
US-4053439-A METAL SALT OF AROMATIC CARBOXYLATE ARMSTRONG CORK COMPANY (US) 1977-10-11 US disclosed