SCHEMBL322393

SCHEMBL322393

O=C1OC(=O)c2c(Br)ccc3cccc1c23

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 9/20 0.62
CYP1B1 Q16678 1/20 0.51
ALDH1A1 P00352 3/20 0.45
CES1 P23141 2/20 0.45
CES2 O00748 1/20 0.45
BCHE P06276 1/20 0.45
MCL1 Q07820 1/20 0.45
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DHFR P00374 2/20 0.38
PARP1 P09874 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29937612 1.00 TYMS (0.62) TYMSCYP1B1ALDH1A1CES1CES2
SCHEMBL27833733 0.79 ALDH1A1 (0.61) TYMSCYP1B1ALDH1A1CES1CES2
SCHEMBL30420926 0.79 ALDH1A1 (0.61) TYMSCYP1B1ALDH1A1CES1CES2
SCHEMBL503034 0.79 TYMS (0.53) TYMSCYP1B1CES1ALOX15TDP1
SCHEMBL6289874 0.79 TYMS (0.62) TYMSCYP1B1ALDH1A1CES1CES2
SCHEMBL22580735 0.79 TYMS (0.62) TYMSCYP1B1ALDH1A1CES1CES2
SCHEMBL30568054 0.79 TYMS (0.62) TYMSALDH1A1CES1CES2BCHE
SCHEMBL7706714 0.79 TYMS (0.62) TYMSALDH1A1CES1CES2BCHE
SCHEMBL4958874 0.79 TYMS (0.62) TYMSALDH1A1CES1CES2BCHE
SCHEMBL4960210 0.79 TYMS (0.62) TYMSCYP1B1ALDH1A1CES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4613796-A1 STAR-SHAPED POLYMERS Evonik Operations GmbH (DE) 2025-09-10 EP claimed
CN-118147301-A Fluorescent probe for simultaneously detecting activity of hydrogen sulfide and telomerase and preparation method thereof 安徽大学 2024-06-07 CN claimed
CN-118146155-A Naphthalimide photoinitiator capable of generating free radicals and organic sulfonic acid as well as preparation method and application thereof 吉林大学 2024-06-07 CN claimed
CN-118126031-A Fluorescent probe for detecting chlorpyrifos and preparation method and application thereof 湘潭大学 2024-06-04 CN claimed
CN-115716803-B Naphthalimide fluorescent probe and application thereof in polarity and viscosity detection 广西大学 2024-05-28 CN claimed
CN-118084786-A Schiff base compound, preparation method and application thereof 安徽省东超科技有限公司 2024-05-28 CN claimed
CN-118084785-A Naphthalimide Schiff base derivative and preparation method and application thereof 安徽省东超科技有限公司 2024-05-28 CN claimed
CN-116217486-B Fluorescent compound and preparation method and application thereof 厦门大学 2024-05-14 CN claimed
CN-118022687-A Detection and removal of Hg2+/Hg+Ion adsorbent and preparation method thereof 萍乡学院 2024-05-14 CN claimed
CN-116332845-B Dialkylamine substituted naphthalimide dye in supercritical CO2In (a) synthesis and dyeing method 大连工业大学 2024-05-03 CN claimed
US-6583248-B1 Methacrylate groups; dental cement AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 2003-06-24 US claimed
CN-1374307-A Luminescent aromatic tetrahydric dianhydride containing naphthalene structure and its prepn UNIV SHANGHAI JIAOTONG (CN) 2002-10-16 CN claimed
EP-1213967-A1 ANTIMICROBIAL POLYMER Avecia Limited (GB) 2002-06-19 EP claimed
WO-2001017356-A1 ANTIMICROBIAL POLYMER AVECIA LIMITED (GB) 2001-03-15 WO claimed
US-6180739-B1 CYCLODEXTRINS WITH ACRYLATE AND ANHYDRIDES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION 2001-01-30 US claimed
EP-0937752-A2 Naphthalimide colorants with improved compatibility in refrigeration and air conditioning lubricants MILLIKEN RESEARCH CORPORATION (US) 1999-08-25 EP claimed
US-5929131-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1999-07-27 US claimed
US-5918269-A LEAK DETECTION COLORANTS IN REFRIGERATION AND AIR CONDITIONING SYSTEMS; REACTION PRODUCT OF 4-HALO-1,8-NAPHTHALIC ANHYDRIDE AND ETHERAMINE MILLIKEN & COMPANY (US) 1999-06-29 US claimed
US-5792821-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1998-08-11 US claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed