Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 15/20 | 0.44 |
| ▸ | ESR1 | P03372 | 10/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867902 | 0.83 | ESR2 (0.47) | ESR2ESR1 | |
| SCHEMBL6867899 | 0.83 | ESR2 (0.47) | ESR2ESR1 | |
| SCHEMBL6866516 | 0.79 | ESR2 (0.44) | ESR2ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL6866518 | 0.79 | ESR2 (0.44) | ESR2ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL6865594 | 0.75 | ESR2 (0.40) | ESR2ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL6865590 | 0.75 | ESR2 (0.40) | ESR2ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL7823288 | 0.72 | SHBG (0.61) | ESR2ESR1SHBGKDM4EALDH1A1 | |
| SCHEMBL6864329 | 0.72 | ESR2 (0.41) | ESR2ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL6864333 | 0.72 | ESR2 (0.41) | ESR2ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL6865603 | 0.69 | KDM4E (0.64) | ESR2ESR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350733-B1 | 4-HYDROXYBENZOPYRAN-2-ONE DERIVATIVES; BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS; SKIN DISORDERS | AVENTIS PHARMA S.A. (FR) | 2002-02-26 | — | — | US | disclosed |