Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16696087 | 0.85 | HTT (0.51) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL16696105 | 0.84 | HPGD (0.56) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL8689214 | 0.84 | ALDH1A1 (0.79) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL1899470 | 0.83 | KDM6B (0.62) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL1902821 | 0.81 | HPGD (0.69) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL28286623 | 0.79 | HPGD (0.50) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL9279236 | 0.79 | ALDH1A1 (0.71) | ALDH1A1HPGDHSD17B10KDM4ERAB9A | |
| SCHEMBL6681562 | 0.78 | APEX1 (0.44) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL16696066 | 0.78 | APEX1 (0.67) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL16696078 | 0.78 | APEX1 (0.51) | ALDH1A1HPGDHSD17B10KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065336-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |
| EP-1228042-A2 | TETRAHYDROQUINOLINE DERIVATIVES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan Sales, Inc. (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001012606-A2 | TETRAHYDROQUINOLINE DERIVATIVES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN SALES, INC. (US) | 2001-02-22 | — | — | WO | disclosed |