Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGAV | P06756 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706968 | 1.00 | ITGB3 (0.44) | ITGB3ITGAVITGA2BSYKKLK7 | |
| SCHEMBL5561128 | 0.86 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL5567560 | 0.85 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL5566427 | 0.83 | SYK (0.45) | ITGB3ITGAVITGA2BSYKCTSL | |
| SCHEMBL5566516 | 0.82 | SYK (0.45) | ITGB3ITGAVITGA2BSYKCTSL | |
| SCHEMBL5567726 | 0.77 | ITGB3 (0.69) | ITGB3ITGAVITGA2B | |
| SCHEMBL14546828 | 0.77 | ITGB3 (0.69) | ITGB3ITGAVITGA2B | |
| SCHEMBL5561642 | 0.76 | ITGB3 (0.70) | ITGB3ITGAVITGA2B | |
| SCHEMBL5562060 | 0.74 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL5562064 | 0.74 | ITGB3 (0.53) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240161-A1 | THIENYLALANINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | Aventis Pharma Deutschland GmbH (DE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001044237-A1 | THIENYLALANINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |