Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706978 | 0.94 | PDE10A (0.48) | PDE10AHCRTR1HCRTR2PDE4BPDE4A | |
| SCHEMBL7709735 | 0.92 | PDE10A (0.52) | PDE10AHCRTR1HCRTR2PDE4BALDH1A1 | |
| SCHEMBL2557257 | 0.85 | PDE10A (0.47) | PDE10APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2560597 | 0.82 | PDE10A (0.52) | PDE10APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2557003 | 0.81 | PDE10A (0.52) | PDE10AHCRTR1HCRTR2PDE4BPDE4A | |
| SCHEMBL2557880 | 0.81 | PDE10A (0.40) | PDE10APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2563284 | 0.80 | PDE10A (0.56) | PDE10APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2563454 | 0.80 | PDE10A (0.51) | PDE10APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2561150 | 0.79 | PDE10A (0.47) | PDE10APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2560840 | 0.79 | PDE10A (0.46) | PDE10APDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |