Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.61 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.61 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.61 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982193 | 1.00 | PNP (0.61) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7707004 | 1.00 | PNP (0.61) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982391 | 0.89 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982393 | 0.89 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL855722 | 0.88 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10438039 | 0.88 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5549318 | 0.87 | PNP (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982109 | 0.87 | PNP (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7198420 | 0.87 | PNP (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982104 | 0.87 | PNP (0.76) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355785-B1 | ENZYME INHIBITORS | ARONEX PHARMACEUTICALS, INC. | 2002-03-12 | — | — | US | claimed |
| US-5646155-A | ADMINISTERING A 9-SUBSTITUTED-N2-PHENYLGUANINE DERIVATIVE | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-07-08 | — | — | US | disclosed |