SCHEMBL855722

SCHEMBL855722

OC[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)C[C@@H]1O

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 1/20 0.64
▸ LMNA P02545 1/20 0.64
▸ TP53 P04637 1/20 0.64
▸ HTT P42858 1/20 0.64
▸ PDE4D Q08499 1/20 0.64
▸ PDE3A Q14432 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.64
▸ RXFP1 Q9HBX9 1/20 0.64
▸ HIF1A Q16665 1/20 0.58
▸ PIM1 P11309 1/20 0.57
▸ CSNK2A2 P19784 1/20 0.57
▸ CSNK2B P67870 1/20 0.57
▸ CSNK2A1 P68400 1/20 0.57
▸ CSNK2A3 Q8NEV1 1/20 0.57
▸ ADRB1 P08588 1/20 0.54
▸ DNMT1 P26358 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438039 1.00 PNP (0.64) PNPLMNATP53HTTPDE4D
SCHEMBL10760495 0.89 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL10760521 0.89 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL10438068 0.89 PNP (0.51) PNPLMNATP53HTTPDE4D
SCHEMBL10438069 0.89 PNP (0.51) PNPLMNATP53HTTPDE4D
SCHEMBL5983822 0.88 PNP (0.67) PNPLMNATP53HTTPDE4D
SCHEMBL5983826 0.88 PNP (0.67) PNPLMNATP53HTTPDE4D
SCHEMBL998385 0.88 PNP (0.78) PNPLMNATP53HTTPDE4D
SCHEMBL3940787 0.88 PNP (0.78) PNPLMNATP53HTTPDE4D
SCHEMBL5981918 0.88 PNP (0.61) PNPLMNATP53HTTPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215615-A1 METHOD FOR EVALUATING DNA-ENCODED LIBRARY NISSAN CHEMICAL CORPORATION (JP) 2025-07-03 — — US claimed
US-20250146060-A1 ECHO AMPLIFICATION: A COMPREHENSIVE SYSTEM OF CHEMISTRY AND METHODS FOR AMPLIFICATION AND DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES CEPHEID 2025-05-08 — — US claimed
US-12084715-B1 Methods and systems for reducing artifactual antisense products 10X GENOMICS, INC. (US) 2024-09-10 — — US claimed
EP-4402284-A2 ECHO AMPLIFICATION: A COMPREHENSIVE SYSTEM OF CHEMISTRY AND METHODS FOR AMPLIFICATION AND DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES Cepheid (US) 2024-07-24 — — EP claimed
US-20230212214-A1 CLEAVABLE DNA-ENCODED LIBRARY NISSAN CHEMICAL CORPORATION (JP) 2023-07-06 — — US claimed
WO-2023095841-A1 METHOD FOR EVALUATING DNA-ENCODED LIBRARY 日産化学株式会社 2023-06-01 — — WO claimed
EP-4159766-A1 CLEAVABLE DNA-ENCODED LIBRARY Nissan Chemical Corporation (JP) 2023-04-05 — — EP claimed
WO-2023043951-A2 ECHO AMPLIFICATION: A COMPREHENSIVE SYSTEM OF CHEMISTRY AND METHODS FOR AMPLIFICATION AND DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES CEPHEID (US) 2023-03-23 — — WO claimed
CN-115461456-A Cleavable DNA-encoded libraries 日产化学株式会社 2022-12-09 — — CN claimed
US-20220282233-A1 Cleavage of Single Stranded DNA Having a Modified Nucleotide NEW ENGLAND BIOLABS, INC. (US) 2022-09-08 — — US claimed
WO-2010030716-A1 DETECTION OF NUCLEIC ACIDS BY OLIGONUCLEOTIDE PROBES CLEAVED IN PRESENCE OF ENDONUCLEASE V KUTYAVIN IGOR (US) 2010-03-18 — — WO claimed
EP-2158462-A1 LOW RADIOCARBON DIETARY SUPPLEMENTS AND METHODS OF MAKING SAME Radiocarb Genetics, Inc. (US) 2010-03-03 — — EP claimed
US-20090318556-A1 BIOMARKERS FOR DETECTING RADIATION EXPOSURE: METHODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2009-12-24 — — US claimed
WO-2008136793-A1 LOW RADIOCARBON DIETARY SUPPLEMENTS AND METHODS OF MAKING SAME WILLIAMS CHRISTOPHER P (US) 2008-11-13 — — WO claimed
US-20070114476-A1 Low radiocarbon nucleotide and amino acid dietary supplements WILLIAMS CHRISTOPHER P 2007-05-24 — — US claimed
WO-2007055860-A2 LOW RADIOCARBON NUCLEOTIDE AND AMINO ACID DIETARY SUPPLEMENTS WILLIAMS CHRISTOPHER P (US) 2007-05-18 — — WO claimed
US-20070104761-A1 Low radiocarbon nucleotide and amino acid dietary supplements RADIOCARB GENETICS, INC. 2007-05-10 — — US claimed
US-5565555-A Nucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analogues GILEAD SCIENCES, INC. (US) 1996-10-15 — — US claimed
EP-0360609-A2 Novel hydrogen phosphonodithioate compositions GILEAD SCIENCES, INC. (US) 1990-03-28 — — EP claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318556-A1 BIOMARKERS FOR DETECTING RADIATION EXPOSURE: METHODS AND USES THEREOF OGG1, UNG, HPRT1 PNP 152/4885LMNA 1709/4885TP53 1716/4885
US-20230212214-A1 CLEAVABLE DNA-ENCODED LIBRARY FEN1, PCNA, UNG PNP 403/4885LMNA 312/4885TP53 181/4885
US-20070104761-A1 Low radiocarbon nucleotide and amino acid dietary supplements DNMT3B, DNMT3A, PCNA PNP 123/4885LMNA 602/4885TP53 226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback