Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045685 | 0.91 | CA14 (0.60) | CA14CA2CA1TDP1ALDH1A1 | |
| SCHEMBL23568851 | 0.88 | CA14 (0.48) | CA14CA2CA1TDP1ALDH1A1 | |
| SCHEMBL20051402 | 0.88 | ALDH1A1 (0.64) | CA14CA2CA1TDP1ALDH1A1 | |
| SCHEMBL28431795 | 0.86 | TDP1 (0.67) | CA14CA2CA1TDP1ALDH1A1 | |
| SCHEMBL7816788 | 0.84 | CA14 (0.55) | CA14CA2CA1TDP1ALDH1A1 | |
| SCHEMBL23465481 | 0.84 | TDP1 (0.51) | CA2CA1TDP1MEN1KMT2A | |
| SCHEMBL20051722 | 0.84 | TDP1 (0.51) | CA2CA1TDP1MEN1KMT2A | |
| SCHEMBL23568858 | 0.83 | CA14 (0.44) | CA14CA2CA1TDP1ALDH1A1 | |
| SCHEMBL12656066 | 0.82 | TDP1 (0.61) | CA2CA1TDP1POLBMEN1 | |
| SCHEMBL23465646 | 0.82 | TDP1 (0.53) | CA2CA1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208109-A2 | NUCLEOSIDE ANALOGUES | NYCOMED AMERSHAM PLC (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001016150-A2 | NUCLEOSIDE ANALOGUES | AMERSHAM PLC (GB) | 2001-03-08 | — | — | WO | disclosed |