Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 10/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156357 | 1.00 | KDM4A (0.47) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL8746938 | 1.00 | KDM4A (0.47) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL1130069 | 0.90 | KDM5A (0.44) | KDM4AHIF1ATET2DOHHKDM4C | |
| SCHEMBL12649156 | 0.88 | KDM4A (0.61) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL10835091 | 0.87 | KDM5A (0.43) | KDM4AHIF1ATET2DOHHKDM4C | |
| SCHEMBL28757040 | 0.85 | KDM4A (0.58) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL1156661 | 0.84 | MMP2 (0.36) | KDM4AHIF1ATET2DOHH | |
| SCHEMBL9435044 | 0.84 | KDM4A (0.50) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL11277722 | 0.83 | — | — | |
| SCHEMBL16352162 | 0.82 | KDM4A (0.39) | KDM4AHIF1ATET2DOHHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | claimed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | claimed |
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | disclosed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0621881-B1 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING & MFG (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0621881-A1 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES). | MINNESOTA MINING & MFG (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5286837-A | Suspending in an amide solvent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| WO-1993015130-A2 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |