Butane

Butane

SCHEMBL7707919

Br.CCCC.CN(C)C

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL27311306 0.94
Butane SCHEMBL7064528 0.94 TSHR (0.36)
Butane SCHEMBL27863151 0.89 DNM1 (0.33)
Butane SCHEMBL27863150 0.89 DNM1 (0.33)
Butane SCHEMBL5129860 0.82 TSHR (0.44)
Butane SCHEMBL27543855 0.82
Butane SCHEMBL8463912 0.82
Butane SCHEMBL8412888 0.82 TSHR (0.44)
Butane SCHEMBL9442188 0.82
Butane SCHEMBL2036217 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348622-B1 CHEMICAL INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
EP-0900785-A2 Vitamin A related compounds and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-10 EP disclosed