Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 5/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.59 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.59 |
| ▸ | GPR183 | P32249 | 1/20 | 0.59 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15960547 | 0.92 | S1PR1 (0.71) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL27583219 | 0.92 | S1PR1 (0.71) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL6259213 | 0.91 | S1PR1 (0.72) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL7613403 | 0.90 | S1PR1 (0.63) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL7622031 | 0.90 | S1PR1 (0.63) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL7708058 | 0.87 | S1PR1 (0.53) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL8496304 | 0.84 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL8499768 | 0.84 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL7621778 | 0.84 | TNNC1 (0.56) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL8500411 | 0.83 | S1PR1 (0.68) | TNNC1S1PR1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372800-B1 | IMMUNOSUPPRESSIVE EFFECT AND IS USEFUL AS AN INHIBITOR FOR THE REJECTION REACTION OCCURRING IN ORGAN OR BONE MARROW TRANSPLANTATION, AND AS A PREVENTIVE OR REMEDY FOR ARTICULAR RHEUMATISM, ATOPIC ECZEMA (DERMATITIS), BEHCET'S DISEASE, | MITSUBISHI PHARMA CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| US-6187821-B1 | SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES | WELFIDE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |