Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.70 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.70 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.70 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.70 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.70 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.70 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.70 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.57 |
| ▸ | OSBP | P22059 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498874 | 1.00 | GPBAR1 (0.70) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7705524 | 0.96 | GPBAR1 (0.69) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL31747501 | 0.95 | GPBAR1 (0.65) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL27276852 | 0.93 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL14812914 | 0.93 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL1011986 | 0.93 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL1011985 | 0.93 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL19313992 | 0.93 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Octane SCHEMBL1954845 | 0.92 | CYP2D6 (0.65) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL19417633 | 0.91 | GPBAR1 (0.62) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359000-B1 | PINE ROOT (DEUTERO MYCETES) FUNGAL METABOLITE, NATURALLY OCCURRING TERPENOID, STEROID, AND POLYKETIDE COMPOUNDS, | MILLENNIUM PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |
| US-6117860-A | NASALLY ADMINISTERING STEROID WHICH BINDS TO A SPECIFIC NEUROEPITHELIAL RECEPTOR FOR ALLEVIATING PREMENSTRUAL TENSION AND ANXIETY | PHERIN PHARMACEUTICALS, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| US-6066627-A | ALTERING BLOOD CONCNETRATION OF LUTEINIZING HORMONE | PHERIN CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| US-6060509-A | ADMINISTERING DOSAGE OF TERPENOID PLANT EXTRACT TO TREAT FUNGAL INFECTION IN MAMMAL | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2000-05-09 | — | — | US | disclosed |
| US-6057439-A | EPOXYSTEROIDS | PHERIN CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5932613-A | PINE ROOT FUNGAL METABOLITE OR ANALOG | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1999-08-03 | — | — | US | disclosed |
| US-5917084-A | PINE ROOT (DEUTERO MYCETES) FUNGAL METABOLITE, NATURALLY OCCURRING TERPENOID COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| WO-1998000121-A1 | ANTICANCER AGENTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| WO-1998000091-A2 | ANTIFUNGAL AGENTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| US-4058538-A | VITAMIN D | THE UPJOHN COMPANY (US) | 1977-11-15 | — | — | US | disclosed |