Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 11/20 | 0.60 |
| ▸ | F2 | P00734 | 9/20 | 0.60 |
| ▸ | F7 | P08709 | 7/20 | 0.48 |
| ▸ | F3 | P13726 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.46 |
| ▸ | F12 | P00748 | 3/20 | 0.46 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435697 | 1.00 | F11 (0.60) | F11F2F7F3F10 | |
| SCHEMBL6439323 | 0.89 | F11 (0.62) | F11F2F7F3F10 | |
| SCHEMBL6438813 | 0.89 | F11 (0.62) | F11F2F7F3F10 | |
| SCHEMBL6438817 | 0.89 | F11 (0.62) | F11F2F7F3F10 | |
| SCHEMBL7711114 | 0.88 | F11 (0.62) | F11F2F7F3F10 | |
| SCHEMBL6436658 | 0.88 | F11 (0.62) | F11F2F7F3F10 | |
| SCHEMBL6436777 | 0.88 | F11 (0.61) | F11F2F7F3F10 | |
| SCHEMBL6435693 | 0.87 | F11 (0.59) | F11F2F7F3F10 | |
| SCHEMBL6435689 | 0.87 | F11 (0.59) | F11F2F7F3F10 | |
| SCHEMBL6440443 | 0.87 | F11 (0.58) | F11F2F7F3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |