Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704892 | 0.89 | — | — | |
| SCHEMBL7710993 | 0.88 | KDM4E (0.30) | ALDH1A1 | |
| SCHEMBL7710851 | 0.87 | AAK1 (0.31) | — | |
| SCHEMBL7711553 | 0.85 | CYP2C19 (0.32) | — | |
| SCHEMBL7708012 | 0.85 | KDM4D (0.35) | — | |
| SCHEMBL7711069 | 0.83 | CYP3A4 (0.31) | — | |
| SCHEMBL7705087 | 0.82 | EDNRA (0.31) | — | |
| SCHEMBL7711431 | 0.81 | PARP1 (0.37) | ALDH1A1 | |
| SCHEMBL7708101 | 0.80 | — | — | |
| SCHEMBL7713262 | 0.79 | USP2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |